hrp0086rfc4.2 | Pathophysiology of Obesity | ESPE2016

Adipocytokines Delay Pubertal Maturation of Human Sertoli Cells

Wagner Isabel V. , Yango Pamela , Svechnikov Konstantin , Tran Nan D. , Soder Olle

Background: Obesity and metabolic syndrome related co-morbidities are increasingly recognized in children. Reproduction is an important target of obesity complications, including adverse effects on spermatogenesis and steroidogenesis in males. Adipocytokines are key players in various complications of obesity.Objective and hypotheses: The aim was to study the potential effects of adipocytokines on Sertoli cell function and possibly link the findings to t...